Publication Details:

Established in 2008

Journal or Publication Title:

Armenian Journal of Physics=Ֆիզիկայի հայկական հանդես

Date of publication:

2016

Volume:

9

Number:

2

ISSN:

1829-1171

Official URL:

Corporate Creators:

Yerevan State University, Department of Radiophysics ; Department of Physics, Sam Houston State University, Huntsville, Texas 77341, USA ; Department of Physics and Basic Science Institute for Cell Damage Control Sogang University, Seoul, Korea

Coverage:

148-153

Abstract:

Near-field scanning microwave microscope (NSMM) is used to readout and visualize homemade 10mer oligonucleotides microarrays of DNA. NSMM instrumentation does not require labeling of target sequences with fluorophores or other tagging groups. Sensitive examination of DNA coverage and high resolution mapping of DNA spots in the microarray were observed by measuring thechange of microwave reflection coefficient (S11) at about 4 GHz operating frequency. The linear dynamicrange for the 10mer nucleotide is over at least 3 orders of magnitude from 0.001pM to 1pM with the detection limit estimated to be approximately 1fM, i.e. 21010 stands/m2.

Date created:

2016-05-01

Format:

pdf

Identifier:

oai:arar.sci.am:23443

Location of original object:

ՀՀ ԳԱԱ Հիմնարար գիտական գրադարան