Publication Details:
Journal or Publication Title:
Armenian Journal of Physics=Ֆիզիկայի հայկական հանդես
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Creator:
A. T. Karapetyan ; Yu. S. Babayan ; M. A. Torosyan ; M. A. Shahinyan
Corporate Creators:
National University of Architecture and Construction of Armenia, Yerevan ; Yerevan State University, Faculty of Biology
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Abstract:
Thermostability of mitoxantrone complexes with DNA of sarcoma 45 and healthy rat liver earlier irradiated by non-thermal (50 μW/cm2) resonant (64.5 GHz and 50.3 GHz) and non-resonant (48.3 GHz) of water hexagonal structure frequencies millimeter electromagnetic waves (MEW) oscillations has been studied. It was shown that at irradiation of solutions by resonant with water hexagonalstructurefrequencies, a dehydration of nucleotides of irradiated DNA and Na+ ions existing in the solution occurs. At relatively low concentrations of mitoxantrone it results in decreasing of thermostability of complexes with DNA, moreover this change is more pronounced at complex-formation with DNA from sarcoma 45 tumor. It was shown that the thermostability of the radiated by non-resonant frequents DNA-MTX complexes does not change.